Article

Immunological Differences in Atopic Dermatitis Across Age Groups: Insights from Single-Cell Multi-Omics

2025-11-25

Abstract excerpt

<h4>Background</h4> Atopic dermatitis (AD) occurs across all ages but presents distinct clinical and immunologic features between children, adults, and older adults. The molecular programs underlying these age-specific immune differences remain poorly understood. <h4>Methods</h4> We performed single-cell multi-omics profiling of peripheral blood mononuclear cells (PBMCs) from 29 AD patients and 29 matched health...

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Literature Corpus work: f18c7b4d-186c-59d3-97e8-ce85c5845201
DOI: 10.1101/2025.11.22.689843

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