Article
Exploratory Single-Cell RNA Sequencing of Peripheral Blood Identifies Candidate Signatures Associated with Alzheimer’s Disease
2026-04-24
Abstract excerpt
<h4>Background: </h4> Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a complex etiology, often diagnosed late in its course. Early detection of AD biomarkers could aid in timely intervention and management. Single-cell RNA sequencing (scRNA-seq) offers a powerful tool to unravel cellular heterogeneity and identify molecular signatures associated with disease states. Here, we employ scRNA...
Topics
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- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- GDF15 and Related Biomarkers
- Genetics and Neurodevelopmental Disorders
- Gut microbiota and health
- Neuroinflammation and Neurodegeneration Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- e620f6a2-3e5d-5f25-a398-6496cb7bec1c
- DOI
- 10.20944/preprints202604.1781.v1
