Article

Cell type-specific complement expression from healthy and diseased retinae

2018-09-10

Abstract excerpt

Retinal degeneration is associated with complement system activation, but retinal sources of complement are unknown. Here, we describe the human and murine complement transcriptomes of Müller cells, microglia/macrophages, vascular cells, neurons and retinal pigment epithelium (RPE) in health and disease. All cell populations expressed c1s, c3, cfb, cfp, cfh and cfi . Murine Müller cells contributed the highest a...

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Literature Corpus work: f35c9427-c5f7-5b5d-b533-a63a82a59990
DOI: 10.1101/413088

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