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Article

Complement System and Potential Therapeutics in Age-Related Macular Degeneration

25 Jun 2021

Abstract excerpt

Age-related macular degeneration (AMD) is a complex multifactorial disease characterized in its late form by neovascularization (wet type) or geographic atrophy of the retinal pigment epithelium cell layer (dry type). The complement system is an intrinsic component of innate immunity. There has been growing evidence that the complement system plays an integral role in maintaining immune surveillance and...

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PMID: 34202223
DOI: 10.3390/ijms22136851

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