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Article

Personal and population genomics of human regulatory variation.

Genome research - 1 Sept 2012

Vernot Benjamin, Stergachis Andrew B, Maurano Matthew T, Vierstra Jeff, Neph Shane, Thurman Robert E, Stamatoyannopoulos John A, Akey Joshua M

Abstract excerpt

The characteristics and evolutionary forces acting on regulatory variation in humans remains elusive because of the difficulty in defining functionally important noncoding DNA. Here, we combine genome-scale maps of regulatory DNA marked by DNase I hypersensitive sites (DHSs) from 138 cell and tissue types with whole-genome sequences of 53 geographically diverse individuals in order to better delimit the patterns...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Sequences, Nucleic Acid

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Source

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Identifiers

PMID: 22955981
DOI: 10.1101/gr.134890.111
PMCID: PMC3431486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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