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Complete Suspension Differentiation of Human Pluripotent Stem Cells into Pancreatic Islets Using Vertical Wheel <sup>®</sup> Bioreactors

2023-08-14

Abstract excerpt

Advanced protocols to produce human pluripotent stem cell (SC)-derived islets show promise in functional, metabolic, and transcriptional maturation of cell therapy product to treat diabetes. Available protocols are either developed as complete planar (2D) or, in later stages, combined with suspension cultures (3D). Despite marked progress, both approaches have clear limitations for scalability, cell loss and batch...

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Literature Corpus work
f3243ef3-49c5-59c4-90b6-c579848867a5
DOI
10.1101/2023.08.09.552676
Open publication

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Complete Suspension Differentiation of Human Pluripotent Stem Cells into Pancreatic Islets Using Vertical Wheel <sup>®</sup> BioreactorsDOI 10.1101/2023.08.09.552676
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