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Robust Bioprocess Design and Evaluation of Commercial Media for the Serial Expansion of Human Induced Pluripotent Stem Cell Aggregate Cultures in Vertical-Wheel Bioreactors

2023-08-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>While pluripotent stem cell (PSC) therapies move toward clinical and commercial applications at a rapid rate, manufacturing reproducibility and robustness are notable bottlenecks in regulatory approval. Therapeutic applications of PSCs require large cell quantities to be generated under highly robust, well-defined, and economically viable conditions. Small-scale...

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Literature Corpus work
78477fd4-dbb3-53b5-9627-69720dcab562
DOI
10.21203/rs.3.rs-3201401/v1
Open publication

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Robust Bioprocess Design and Evaluation of Commercial Media for the Serial Expansion of Human Induced Pluripotent Stem Cell Aggregate Cultures in Vertical-Wheel BioreactorsDOI 10.21203/rs.3.rs-3201401/v1
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