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A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells

18 May 2012

Abstract excerpt

Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated that hESC can be directed to differentiate into pancreatic progenitors that mature into functional glucose-responsive, insulin-secreting cells in vivo. In this study we...

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PMID: 22623968
DOI: 10.1371/journal.pone.0037004

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