Article
A perfect islet: reviewing recent protocol developments and proposing strategies for stem cell derived functional pancreatic islets
31 Mar 2025
Abstract excerpt
The search for an effective cell replacement therapy for diabetes has driven the development of "perfect" pancreatic islets from human pluripotent stem cells (hPSCs). These hPSC-derived pancreatic islet-like β cells can overcome the limitations for disease modelling, drug development and transplantation therapies in diabetes. Nevertheless, challenges remain in generating fully functional and mature β cells from...
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