Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An arduous journey from human pluripotent stem cells to functional pancreatic β cells

4 May 2017

Abstract excerpt

Type 1 and type 2 diabetes are caused by a destruction and decrease in the number of functional insulin-producing β cells, respectively; therefore, the generation of functional β cells from human embryonic stem cells and human induced pluripotent stem cells, collectively known as human pluripotent stem cells (hPSCs), for potential cell replacement therapy and disease modelling is an intensely investigated area....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28474496
DOI: 10.1111/dom.12996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An arduous journey from human pluripotent stem cells to functional pancreatic β cellsPMID 28474496Read ↗

Exploring optimal protocols for generating and preserving glucose-responsive insulin-secreting progenitor cells derived from human pluripotent stem cellsSemantic proximity Read ↗

A perfect islet: reviewing recent protocol developments and proposing strategies for stem cell derived functional pancreatic isletsSemantic proximity Read ↗

Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directionsSemantic proximity Read ↗

Advances Toward Engineering Functionally Mature Human Pluripotent Stem Cell-Derived β CellsSemantic proximity Read ↗

Manufacturing clinical‐grade human induced pluripotent stem cell‐derived beta cells for diabetes treatmentSemantic proximity Read ↗

Generation of β cells from human pluripotent stem cells: Are we there yet?Semantic proximity Read ↗

Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?Semantic proximity Read ↗

Converting human pluripotent stem cells into β-cells: recent advances and future challengesSemantic proximity Read ↗

Concise Review: Pluripotent Stem Cell-Based Regenerative Applications for Failing β-Cell FunctionSemantic proximity Read ↗

High-purity stem cell-derived β-cells recapitulate key transcriptional and functional features of human isletsSemantic proximity Read ↗

Human Pluripotent Stem Cells to Model Islet Defects in Diabetes.Semantic proximity Read ↗

Pancreatic Beta Cell Differentiation From Human Pluripotent Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.