Article

Mitochondrial protein import stress augments α-synuclein aggregation and neural damage independent of bioenergetics

2025-08-18

Abstract excerpt

<title>Abstract</title> <p>Genetic and environmental factors are known to converge on mitochondria to cause Parkinson’s disease (PD). However, the mechanisms by which mitochondrial dysfunction contributes to neurodegeneration remain incompletely understood. Non-bioenergetic pathways of the mitochondria are increasingly appreciated, but confounding bioenergetic defects are a major barrier to experimental validatio...

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Literature Corpus work: f31f6ba8-bfd8-5bbe-9307-66481154df57
DOI: 10.21203/rs.3.rs-3136613/v1

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