Article

Bortezomib Promotes Neutrophil-Mediated Bacterial Clearance in Sepsis by Inhibiting Plasmablast Activation

2025-10-01

Abstract excerpt

<h4>Background: </h4> and Purpose: Sepsis induces immunosuppression, contributing to high mortality. Plasmablasts, a regulatory B cell subset that expands during sepsis, are known to suppress immune function, but the consequences of their specific removal on sepsis outcome remain unclear. This study aimed to determine whether depleting plasmablasts could improve sepsis prognosis and to investigate the underlying m...

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Literature Corpus work: f31c1a96-3a13-5ec5-a6ba-9c6454f1f3f3
DOI: 10.22541/au.175934360.07145019/v1

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Bortezomib Promotes Neutrophil-Mediated Bacterial Clearance in Sepsis by Inhibiting Plasmablast ActivationDOI 10.22541/au.175934360.07145019/v1Read

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