Article

The Post-Septic Peripheral Myeloid Compartment Reveals Unexpected Diversity in Myeloid-Derived Suppressor Cells

2024-01-07

Abstract excerpt

Sepsis engenders distinct host immunologic changes that include the expansion of myeloid-derived suppressor cells (MDSCs). These cells play a physiologic role in tempering acute inflammatory responses but can persist in patients who develop chronic critical illness. The origins and lineage of these MDSC subpopulations were previously assumed to be discrete and unidirectional; however, these cells exhibit a dynamic...

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Literature Corpus work: 004d7c8a-2f6d-5ae2-ad69-8faa0e43126c
DOI: 10.1101/2024.01.05.24300902

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