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Article

Development of Exhausted Memory Monocytes and Underlying Mechanisms.

Frontiers in immunology - 1 Jan 2021

Pradhan Kisha, Yi Ziyue, Geng Shuo, Li Liwu

Abstract excerpt

Pathogenic inflammation and immuno-suppression are cardinal features of exhausted monocytes increasingly recognized in septic patients and murine models of sepsis. However, underlying mechanisms responsible for the generation of exhausted monocytes have not been addressed. In this report, we examined the generation of exhausted primary murine monocytes through prolonged and repetitive challenges with high dose...

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Identifiers

PMID: 34777396
DOI: 10.3389/fimmu.2021.778830
PMCID: PMC8583871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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