Septic Shock Shapes B Cell Response toward an Exhausted-like/Immunoregulatory Profile in Patients

Abstract excerpt

Abstract Septic shock is accompanied by the development of immune dysfunctions whose intensity and duration are associated with increased risk of secondary infections and mortality. Although B lymphocytes play a pivotal role in the immune response to infections, no comprehensive exploration of circulating B cell status has been performed during the immunosuppressive phase of septic shock. Thus, our aim was to...

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