Article

FLT3 inhibitors and hematopoietic cell transplantation prolong survival in patients with FLT3-ITD-positive AML

2024-08-26

Abstract excerpt

<title>Abstract</title> <p>Acute myeloid leukemia (AML) is an aggressive hematological malignancy with genetic alterations. The FMS-like tyrosine kinase 3 (FLT3) gene is frequently mutated in adult <italic>de novo</italic> AML, with two types of mutations: internal tandem duplication (ITD) and point mutations in the tyrosine kinase domain. This study aimed to investigate the impact of FLT3 inhibitors and hematopo...

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Literature Corpus work: f3150c95-77a0-5d7f-ac8c-b8acc3da2993
DOI: 10.21203/rs.3.rs-4767599/v1

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