Article
Prognostic Significance of Fms-Like Tyrosine Kinase 3 Internal Tandem Duplication Mutation in Non-Transplant Adult Patients with Acute Myeloblastic Leukemia: A Systematic Review and Meta-Analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2020
Rinaldi Ikhwan, Louisa Melva, Wiguna Fikri Ichsan, Budiani Elizabeth, Mahardhika Jeffrey Christian, Hukmi Khairul
Abstract excerpt
BACKGROUND: Fms-like tyrosine kinase-3, internal tandem duplication (FLT3-ITD) mutation, is a known predictor for worse outcome in patients with acute myeloblastic leukemia (AML). However, the prognostic significance of FLT3-ITD mutation in adult, non-transplant patients is still unclear therefore we conducted a systematic review and meta-analysis to explain this issue. The main outcome was overall survival (OS),...
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