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[Pathogenesis and treatment of acute myeloid leukemia with FLT3 mutations].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2024

Ishikawa Yuichi

Abstract excerpt

FLT3 mutations are the most frequently identified genetic abnormalities in adult acute myeloid leukemia (AML) patients, accounting for approximately 30%. FLT3-ITD mutation specifically is considered as a poor prognostic factor in AML, and allogeneic hematopoietic cell transplantation in first remission is recommended for younger patients. The recent clinical introduction of FLT3 inhibitors has been reported to...

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PMID: 39358294
DOI: 10.11406/rinketsu.65.945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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