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Improved Posttransplant Outcomes in Recent Years for AML Patients with FLT3-ITD and Wild-type NPM1: A Report from the EBMT Acute Leukemia Working Party.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2023

Bazarbachi Ali, Labopin Myriam, Gedde-Dahl Tobias, Remenyi Peter, Forcade Edouard, Kröger Nicolaus, Socié Gerard, Craddock Charles, Bourhis Jean Henri, Versluis Jurjen, Yakoub-Agha Ibrahim, Salmenniemi Urpu, El-Cheikh Jean, Bug Gesine, Esteve Jordi, Nagler Arnon, Ciceri Fabio, Mohty Mohamad

Abstract excerpt

PURPOSE: Allogeneic hematopoietic cell transplantation (allo-HCT) is recommended in first complete remission (CR1) in patients with acute myeloid leukemia (AML) harboring FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD). We assessed changes over time in transplant characteristics and outcomes in patients with AML age 60 years and younger with a FLT3-ITD. EXPERIMENTAL DESIGN: We identified 1,827...

Topics

Adult
Humans
Adolescent
Young Adult
Middle Aged
Nuclear Proteins
Nucleophosmin
fms-Like Tyrosine Kinase 3
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hematopoietic Stem Cell Transplantation

Leukemia, Myeloid, Acute

Prognosis

Retrospective Studies

Source

Identifiers

PMID: 37603683
DOI: 10.1158/1078-0432.CCR-23-0954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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