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Article

[Breakthroughs in FLT3-mutated acute myeloid leukemia treatments].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2023

Najima Yuho

Abstract excerpt

FMS-like tyrosine kinase 3 (FLT3) mutation is present in 25% of acute myeloid leukemia (AML) cases. It is associated with poor prognosis due to a high relapse rate and short remission duration. Consequently, various FLT3 inhibitors were developed. Two second-generation FLT3 inhibitors, including gilteritinib and quizartinib, are used for treating relapsed/refractory FLT3-mutated AML. Additionally, in May 2023,...

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Source

Identifiers

PMID: 37793868
DOI: 10.11406/rinketsu.64.932

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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