Article
Allogeneic transplant for FLT3 - ITD mutated AML: a focus on FLT3 inhibitors before, during, and after transplant
1 Jan 2019
Abstract excerpt
FMS-like tyrosine kinase 3 ( FLT3) mutations are one of the most frequently encountered genetic alterations in acute myeloid leukemia (AML), and are generally associated with unfavorable outcomes. Several tools are currently available to provide an accurate prognosis for patients with these mutations, including FLT3 mutation type (internal tandem duplication versus tyrosine kinase domain), mutation allelic ratio...
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