Article

Stretch Regulates Alveologenesis and Homeostasis Via Mesenchymal G <sub>αq/11</sub> -Mediated TGFβ2 Activation

2020-09-07

Abstract excerpt

Alveolar development and repair require tight spatiotemporal regulation of numerous signalling pathways that are influenced by chemical and mechanical stimuli. Mesenchymal cells play key roles in numerous developmental processes. Transforming growth factor-β (TGFβ) is essential for alveologenesis and lung repair, and the G protein α subunits G αq and G α11 (G αq/11 ) transmit mechanical and chemical signals to...

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Literature Corpus work: f30cf5bd-c5fe-55aa-8003-56c315c50843
DOI: 10.1101/2020.09.06.284778

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