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Article

Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2007

Braunersreuther Vincent, Zernecke Alma, Arnaud Claire, Liehn Elisa A, Steffens Sabine, Shagdarsuren Erdenechimeg, Bidzhekov Kiril, Burger Fabienne, Pelli Graziano, Luckow Bruno, Mach François, Weber Christian

Abstract excerpt

OBJECTIVE: Chemokines and their receptors are crucially involved in the development of atherosclerotic lesions by directing monocyte and T cell recruitment. The CC-chemokine receptors 1 (CCR1) and 5 (CCR5) expressed on these cells bind chemokines implicated in atherosclerosis, namely CCL5/RANTES. Although general blockade of CCL5 receptors reduces atherosclerosis, specific roles of CCR1 and CCR5 have not been...

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Share to Cholesterol, Dietary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17138939
DOI: 10.1161/01.ATV.0000253886.44609.ae

Genes

CCR5
CCL5
CCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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