Article

Modulation of the gastrointestinal immune environment by macrophage Migration Inhibitory Factors (MIF) and helminth-derived cytokine homologues of MIF

2020-01-01

Abstract excerpt

Macrophage Migration Inhibitory Factor (MIF) is a pleotropic cytokine first discovered over 50 years ago. MIF and many MIF-like proteins contain an evolutionarily conserved proline residue that confers an enigmatic tautomerase activity. Mammalian MIF proteins also contain an additional oxidoreductase domain whose activity is abrogated by substitution of two critical cysteine residues at position 57 and 60. MIF is...

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Literature Corpus work: f2b7aaac-3fee-5674-b628-b366e87aa03f
DOI: 10.15123/uel.88vx8

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