Article
The gut microbiota-derived metabolite indole regulates cytoskeletal functions and virulence in <i>Entamoeba histolytica</i>
2025-08-01
Abstract excerpt
Entamoeba histolytica is a pathogenic amoeba that inhabits the human large intestine and causes amoebiasis. E. histolytica interacts with both the intestinal microbiota and the metabolites they produce. These bacterial metabolites play a crucial role in shaping the virulence and stress resistance of E. histolytica . One such metabolite, indole, is synthesized by bacteria from tryptophan and functions as a key si...
Topics
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- Amoebic Infections and Treatments
- Bacterial Genetics and Biotechnology
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Gut microbiota and health
- Parasitic Infections and Diagnostics
- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
Identifiers and source
- Literature Corpus work
- c0966458-6b60-5cac-aa85-156480f5d28c
- DOI
- 10.1101/2025.08.01.668081