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Article

Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2008

Flores Marcos, Saavedra Rafael, Bautista Rocio, Viedma Rubi, Tenorio Eda P, Leng Lin, Sánchez Yuriko, Juárez Imelda, Satoskar Anjali A, Shenoy Asha S, Terrazas Luis I, Bucala Richard, Barbi Joseph, Satoskar Abhay R, Rodriguez-Sosa Miriam

Abstract excerpt

Macrophage migration inhibitory factor (MIF) exerts either a protective or a deleterious role in the immune response to different pathogens. We analyzed herein the role of MIF in the host control of toxoplasmosis using MIF(-/-) mice backcrossed to either the BALB/c or the C57BL/6 genetic backgrounds. Both, wild-type (WT) BALB/c and MIF(-/-) BALB/c mice were susceptible to infection with highly virulent RH as well...

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Identifiers

PMID: 18606868
DOI: 10.1096/fj.08-111666
PMCID: PMC2537436

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii.PMID 18606868Read ↗

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