Article

Histone H4 aggravates inflammatory injury through TLR4 in chlorine gas-induced acute respiratory distress syndrome

2020-09-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Chlorine gas (Cl 2 ) exposure remains a public health concern in household, occupational, and transportation accidents around the world. The death rate associated with acute respiratory distress syndrome (ARDS) caused by high concentrations of Cl 2 is very high, mainly because the pathogenesis of ARDS remains unclear. Histone H4 has been identified as an importa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f2a55eac-1b8b-5f11-9a4c-18f2ee95af45
DOI: 10.21203/rs.3.rs-21326/v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Histone H4 aggravates inflammatory injury through TLR4 in chlorine gas-induced acute respiratory distress syndromeDOI 10.21203/rs.3.rs-21326/v3Read

A dual role for CRTH2 in acute lung injurySemantic proximity Read

TLR4 knock out alleviate both lung and liver inflammation caused by short-time exposure to PM2.5Semantic proximity Read

Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed MiceSemantic proximity Read

Targeting extranuclear histones to alleviate acute and chronic inflammationSemantic proximity Read

Extracellular histones stimulate collagen expression and potentially promote liver fibrogenesis via TLR4-MyD88 signalling pathwaySemantic proximity Read

Functional genomics of chlorine-induced acute lung injury in mice.Semantic proximity Read

Integrative assessment of chlorine-induced acute lung injury in mice.Semantic proximity Read

The role of extracellular histones in critical illness and their application in acute pancreatitisSemantic proximity Read

The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles.Semantic proximity Read

Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in miceSemantic proximity Read

Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injurySemantic proximity Read

Apolipoprotein A4 regulates the immune response in carbon tetrachloride-induced chronic liver injury in mice.Semantic proximity Read