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Article

The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles.

Archives of toxicology - 1 May 2006

Inoue Ken-Ichiro, Takano Hirohisa, Yanagisawa Rie, Hirano Seishiro, Ichinose Takamichi, Shimada Akinori, Yoshikawa Toshikazu

Abstract excerpt

Although several studies have demonstrated that airway exposure to diesel exhaust particles (DEP) induces lung inflammation, the signaling pathways involved in the pathogenesis remain unclear. Toll-like receptors (TLRs) are generally accepted to be pathogen recognition receptors in mammalians. In the present study, we investigated the role of TLR-4 in DEP-induced lung inflammation and cytokine expression in the...

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PMID: 16254717
DOI: 10.1007/s00204-005-0040-6

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MIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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