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Common and rare variants in HFE are not associated with Parkinson’s disease in Europeans

2020-10-26

Abstract excerpt

A recent study suggested that the p.H63D variant in HFE , a gene involved in iron homeostasis, may modify α-synuclein pathology, the pathological hallmark of Parkinson’s disease (PD). If indeed this gene and specific variant are involved in PD, we expect to find differential distribution of HFE variants when comparing PD patients and controls. We analyzed genome-wide association study (GWAS) data from 14,671 PD pa...

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Identifiers and source

Literature Corpus work
f277ad0c-a97c-593f-b9e9-b3bd48d8c5d2
DOI
10.1101/2020.10.22.20217190
Open publication

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Common and rare variants in HFE are not associated with Parkinson’s disease in EuropeansDOI 10.1101/2020.10.22.20217190
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