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Article

Screening for mutations of the HFE gene in Parkinson's disease patients with hyperechogenicity of the substantia nigra.

Neuroscience letters - 16 Oct 2006

Akbas Nilgün, Hochstrasser Helmine, Deplazes Joelle, Tomiuk Jürgen, Bauer Peter, Walter Uwe, Behnke Stefanie, Riess Olaf, Berg Daniela

Abstract excerpt

Iron mediated oxidative stress is known to contribute to the neurodegenerative process in Parkinson's disease (PD). Although there are hints that genes involved in brain iron metabolism might be involved in the pathogenesis of PD in some instances, it is still not known whether the increase in brain iron content constitutes a primary or secondary event in the disease cascade. Recent studies on the role of...

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PMID: 16935420
DOI: 10.1016/j.neulet.2006.07.070

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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