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Article

The Cys282Tyr polymorphism in the HFE gene in Australian Parkinson's disease patients.

Neuroscience letters - 19 Jul 2002

Buchanan D D, Silburn P A, Chalk J B, Le Couteur D G, Mellick G D

Abstract excerpt

Iron homeostasis is altered in Parkinson's disease (PD). The HFE protein is an important regulator of cellular iron homeostasis and variations within this gene can result in iron overload and the disorder known as hereditary haemochromatosis. We studied the Cys282Tyr single nucleotide polymorphism as a genetic risk factor for PD in two distinct and separately collected cohorts of Australian PD patients and...

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Source

Identifiers

PMID: 12098643
DOI: 10.1016/s0304-3940(02)00398-1

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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