Article

Chronic aromatase inhibition increases ventral hippocampal neurogenesis in middle-aged female mice

2018-10-04

Abstract excerpt

Letrozole, a third-generation aromatase inhibitor, prevents the production of estrogens in the final step in conversion from androgens. Due to its efficacy at suppressing estrogens, letrozole has recently taken favor as a first-line adjuvant treatment for hormone-responsive breast cancer in middle-aged women. Though patient response to letrozole has generally been positive, there is conflicting evidence surroundin...

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Literature Corpus work: f229f23d-f3ab-52f9-aa6f-5c1b88fe6c3c
DOI: 10.1101/434662

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