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Article

ERRγ Ligand Regulates Adult Neurogenesis and Depression-like Behavior in a LRRK2-G2019S-associated Young Female Mouse Model of Parkinson's Disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics - 1 Jul 2022

Kim Hyo In, Lim Juhee, Choi Hyo-Jung, Kim Seok-Ho, Choi Hyun Jin

Abstract excerpt

Adult neurogenesis, a process controlling the proliferation to maturation of newly generated neurons in the post-developmental brain, is associated with various brain functions and pathogenesis of neuropsychological diseases, such as Parkinson's disease (PD) and depression. Because orphan nuclear receptor estrogen-related receptor γ (ERRγ) plays a role in the differentiation of neuronal cells, we investigated...

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Identifiers

PMID: 35614294
DOI: 10.1007/s13311-022-01244-5
PMCID: PMC9587185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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