Article

Retention time and fragmentation predictors increase confidence in variant peptide identification

2023-04-01

Abstract excerpt

Precision medicine focuses on adapting care to the individual profile of patients, e.g. accounting for their unique genetic makeup. Being able to account for the effect of genetic variation on the proteome holds great promises towards this goal. However, identifying the protein products of genetic variation using mass spectrometry has proven very challenging. Here we show that the identification of variant peptide...

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Literature Corpus work: f1c55d02-7147-522f-ba5b-53cad796470f
DOI: 10.1101/2023.03.29.534843

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