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Article

Retention Time and Fragmentation Predictors Increase Confidence in Identification of Common Variant Peptides.

Journal of proteome research - 6 Oct 2023

Skiadopoulou Dafni, Vašíček Jakub, Kuznetsova Ksenia, Bouyssié David, Käll Lukas, Vaudel Marc

Abstract excerpt

Precision medicine focuses on adapting care to the individual profile of patients, for example, accounting for their unique genetic makeup. Being able to account for the effect of genetic variation on the proteome holds great promise toward this goal. However, identifying the protein products of genetic variation using mass spectrometry has proven very challenging. Here we show that the identification of variant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37656829
DOI: 10.1021/acs.jproteome.3c00243
PMCID: PMC10563157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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