Article

Quality control of variant peptides identified through proteogenomics- catching the (un)usual suspects

2023-06-03

Abstract excerpt

Variant peptides resulting from translation of single nucleotide polymorphisms (SNPs) can lead to aberrant or altered protein functions and thus hold translational potential for disease diagnosis, therapeutics and personalized medicine. Variant peptides detected by proteogenomics are fraught with high number of false positives. Class-specific FDR along with ad-hoc post-search filters have been employed to tackle t...

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Literature Corpus work: 95a0be16-f448-58af-aa50-61d284d41566
DOI: 10.1101/2023.05.31.542998

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