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Article

Improving gene annotation using peptide mass spectrometry.

Genome research - 1 Feb 2007

Tanner Stephen, Shen Zhouxin, Ng Julio, Florea Liliana, Guigó Roderic, Briggs Steven P, Bafna Vineet

Abstract excerpt

Annotation of protein-coding genes is a key goal of genome sequencing projects. In spite of tremendous recent advances in computational gene finding, comprehensive annotation remains a challenge. Peptide mass spectrometry is a powerful tool for researching the dynamic proteome and suggests an attractive approach to discover and validate protein-coding genes. We present algorithms to construct and efficiently...

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Identifiers

PMID: 17189379
DOI: 10.1101/gr.5646507
PMCID: PMC1781355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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