Article

Decoding the regulatory role and epiclonal dynamics of DNA methylation in 1482 breast tumours

2018-01-01

Abstract excerpt

Breast cancer is a clinically and molecularly heterogeneous disease displaying distinct therapeutic responses. Although recent studies have explored the genomic and transcriptomic landscapes of breast cancer, the epigenetic architecture has received less attention. To address this, an optimised Reduced Representation Bisulfite Sequencing protocol was performed on 1482 primary breast tumours (and 237 matched adjace...

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Literature Corpus work: f18d73c2-ae00-5406-adc2-2ceffda242f1
DOI: 10.17863/cam.22074

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