Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimating breast tissue-specific DNA methylation age using next-generation sequencing data

12 Mar 2020

Abstract excerpt

Abstract Background DNA methylation (DNAm) age has been widely accepted as an epigenetic biomarker for biological aging. Emerging evidence suggests that DNAm age can be tissue-specific and female breast tissue ages faster than other parts of the body. The Horvath clock, which estimates DNAm age across multiple tissues, has been shown to be poorly calibrated in breast issue. We aim to develop a model to estimate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32164769
DOI: 10.1186/s13148-020-00834-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimating breast tissue-specific DNA methylation age using next-generation sequencing dataPMID 32164769Read ↗

Increased epigenetic age in normal breast tissue from luminal breast cancer patientsSemantic proximity Read ↗

DNA methylation age in paired tumor and adjacent normal breast tissue in Chinese women with breast cancerSemantic proximity Read ↗

DNA methylation accelerated age as captured by epigenetic clocks influences breast cancer riskSemantic proximity Read ↗

DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.Semantic proximity Read ↗

DNA-methylation age and accelerated epigenetic aging in blood as a tumor marker for predicting breast cancer susceptibility.Semantic proximity Read ↗

Epigenetic clock detected a breast cancer mitosis subtype with improved immunotherapySemantic proximity Read ↗

Methylation-Based Biological Age and Breast Cancer RiskSemantic proximity Read ↗

Epigenetic age prediction drifts resulting from next-generation methylation arraysSemantic proximity Read ↗

DNA Methylation as a Biomarker of Aging in Epidemiologic Studies.Semantic proximity Read ↗

Applicability of epigenetic age models to next-generation methylation arraysSemantic proximity Read ↗

Decelerated DNA methylation age predicts poor prognosis of breast cancerSemantic proximity Read ↗

DNA methylation age of human tissues and cell types.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.