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Article

Epigenetic modifications in breast cancer and their role in personalized medicine.

The American journal of pathology - 1 Oct 2013

Stefansson Olafur A, Esteller Manel

Abstract excerpt

In cancer, the overall patterns of epigenetic marks are severely distorted from the corresponding normal cell type. It is now well established that these changes can contribute to cancer development through inactivation of tumor suppressor genes and, conversely, through activation of oncogenes. Recent technological advances have enabled epigenome-wide analyses of cancers that are yielding unexpected findings. The...

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PMID: 23899662
DOI: 10.1016/j.ajpath.2013.04.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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