Article

A post-mortem investigation of the locus coeruleus-noradrenergic system in resilience to childhood abuse

2025-03-24

Abstract excerpt

Childhood abuse (CA) is one of the strongest lifetime predictors of major depressive disorder (MDD) and suicide. However, some individuals exposed to CA are resilient, avoiding the development of psychopathology. Recently, the locus coeruleus-noradrenergic (LC-NE) system has been involved in resilience following stressful events at adulthood. We investigated how a history of CA affects the integrity of the LC-NE s...

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Literature Corpus work: f125d45d-2782-5fa0-a9a2-194335a1629e
DOI: 10.1101/2025.03.22.644719

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