Article

Serotonergic plasticity in the dorsal raphe nucleus characterizes susceptibility and resilience to anhedonia

2019-07-30

Abstract excerpt

<h4>ABSTRACT</h4> Chronic stress induces anhedonia in susceptible, but not resilient individuals, a phenomenon observed in humans as well as animal models, but the molecular mechanisms underlying susceptibility and resilience are not well understood. We hypothesized that the serotonergic system, which is implicated in stress, reward and antidepressant therapy, may play a role. We found that plasticity of the sero...

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Literature Corpus work: 34d61cf8-97d2-594e-bdc4-7294765f805b
DOI: 10.1101/719286

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