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Article

Altered miRNA expression network in locus coeruleus of depressed suicide subjects

23 Jun 2017

Abstract excerpt

Norepinephrine (NE) is produced primarily by neurons in the locus coeruleus (LC). Retrograde and ultrastructural examinations reveal that the core of the LC and its surrounding region receives afferent projections from several brain areas which provide multiple neurochemical inputs to the LC with changes in LC neuronal firing, making it a highly coordinated event. Although NE and mediated signaling systems have...

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PMID: 28663595
DOI: 10.1038/s41598-017-04300-9

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