Article

The Drosophila MOZ homolog Enok controls Notch-dependent induction of the RUNX gene <i>lozenge</i> independently of its histone-acetyl transferase activity

2020-07-28

Abstract excerpt

The human KAT6 lysine acetyltransferase MOZ has been shown to be an essential player in the field of normal and malignant hematopoiesis. It belongs to a highly conserved family of epigenetic factors and remodels chromatin by acetylating histone tails in association with its partners of the ING5 complex. Here, we report that its Drosophila counterpart Enok is required during larval hematopoiesis to control the Notc...

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Literature Corpus work: f116cfa6-ddce-5326-9571-0ade1ade95cf
DOI: 10.1101/2020.07.27.222620

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