Article
Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1.
Genes & development - 15 May 1996
Daga A, Karlovich C A, Dumstrei K, Banerjee U
Abstract excerpt
The lozenge (lz) gene encodes a transcription factor involved in prepatterning photoreceptor precursors in the developing Drosophila eye. The central region of the predicted Lz protein product is homologous to AML1, a transcription factor associated with human leukemias, and to the Drosophila protein Runt. We show here that Lz plays a crucial role in governing the fate of two groups of cells that are born in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
