Article
Specification of Drosophila hematopoietic lineage by conserved transcription factors.
Science (New York, N.Y.) - 7 Apr 2000
Lebestky T, Chang T, Hartenstein V, Banerjee U
Abstract excerpt
Two major classes of cells observed within the Drosophila hematopoietic repertoire are plasmatocytes/macrophages and crystal cells. The transcription factor Lz (Lozenge), which resembles human AML1 (acute myeloid leukemia- 1) protein, is necessary for the development of crystal cells during embryonic and larval hematopoiesis. Another transcription factor, Gcm (glial cells missing), has previously been shown to be...
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