Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.

PLoS biology - 1 Aug 2004

Ransom David G, Bahary Nathan, Niss Knut, Traver David, Burns Caroline, Trede Nikolaus S, Paffett-Lugassy Noelle, Saganic Walter J, Lim C Anthoney, Hersey Candace, Zhou Yi, Barut Bruce A, Lin Shuo, Kingsley Paul D, Palis James, Orkin Stuart H, Zon Leonard I

Abstract excerpt

Hematopoiesis is precisely orchestrated by lineage-specific DNA-binding proteins that regulate transcription in concert with coactivators and corepressors. Mutations in the zebrafish moonshine (mon) gene specifically disrupt both embryonic and adult hematopoiesis, resulting in severe red blood ce...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Codon, Terminator

Share to Erythrocytes

Share to Hematopoiesis

Share to Hematopoietic Stem Cells

Share to Heterochromatin

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15314655
DOI: 10.1371/journal.pbio.0020237
PMCID: PMC509301

Genes

TRIM33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15314655-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.PMID 15314655Read ↗

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.Semantic proximity Read ↗

Generation of mice with a conditional allele for Trim33.Semantic proximity Read ↗

MEIS1 regulates early erythroid and megakaryocytic cell fateSemantic proximity Read ↗

A role for the transcription intermediary factor 2 in zebrafish myelopoiesis.Semantic proximity Read ↗

A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesisSemantic proximity Read ↗

Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafishSemantic proximity Read ↗

cpsf1 is required for definitive HSC survival in zebrafish.Semantic proximity Read ↗

Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic RegulatorsSemantic proximity Read ↗

Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiationSemantic proximity Read ↗

Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islandsSemantic proximity Read ↗

NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal.Semantic proximity Read ↗

Gfi-1 Oncoproteins in HematopoiesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.