Article

RNA <i>in situ</i> conformation sequencing reveals novel long-range RNA structures with impact on splicing

2022-11-07

Abstract excerpt

Over past years, long-range RNA structure has emerged as a factor that is fundamental to alternative splicing regulation. Since an increasing number of human disorders are now being associated with splicing defects, it is essential to develop methods that assess long-range RNA structure experimentally. RNA in situ conformation sequencing (RIC-seq) is the method that recapitulates RNA structure within physiologica...

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Literature Corpus work: f0fff099-95ea-5f28-bcf9-6b463b4d59bb
DOI: 10.1101/2022.11.07.515435

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