Article

<i>In-silico</i> modeling and interpretation of RBP binding disentangle m <sup>6</sup> A-RBP interaction

2024-11-25

Abstract excerpt

RNA binding protein (RBP) binding and N 6 -methyladenosine (m 6 A) are both essential post-transcriptional regulatory layers for RNA fate decisions. However, the intricate mechanism underlying the interaction between m 6 A and RBP binding remains underexplored. Here, we develop TransRBP, an interpretable deep learning framework, to model the base-resolution binding of RBPs from RNA sequences and to subsequently...

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Literature Corpus work: 7f20cd00-1389-5c39-8d6b-a01ad657f38d
DOI: 10.1101/2024.11.23.624962

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<i>In-silico</i> modeling and interpretation of RBP binding disentangle m <sup>6</sup> A-RBP interactionDOI 10.1101/2024.11.23.624962Read

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