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Tumor Immune Evasion: Hiding as “Cold” Tumors and Resisting as “Hot” Tumors

2025-12-22

Abstract excerpt

Tumor evolution under immune pressure follows the logic of cancer immunoediting—elimination, equilibrium, and escape—in which immune surveillance removes highly immunogenic clones while selecting for variants capable of persistence and progression. Clinically, this evolutionary outcome is often operationalized as an immune-phenotype continuum, frequently simplified into “hot” (immune-inflamed) and “cold” (immune-e...

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Literature Corpus work
3ced0056-b9e4-55a8-940b-5541c706bb3c
DOI
10.20944/preprints202512.1842.v1
Open publication

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